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Prisma Pro Software Free 58: Features, Benefits, Installation, and Usage



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Prisma Pro Software Free 58



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Filters are a predefined combination of search terms developed to identify references with a specific content, such as a particular type of study design (e.g., randomized controlled trials) [106], populations (e.g., the elderly), or a topic (e.g., heart failure) [107]. They often consist of a combination of subject headings, free-text terms, and publication types [107]. For systematic reviews, filters are generally recommended for use instead of limits built into databases, as discussed in Item 9, because they provide the much higher sensitivity (Table 2) required for a comprehensive search [108].


Databases contain significant overlap in content. When searching in multiple databases and additional information sources, as is necessary for a systematic review, authors often employ a variety of techniques to reduce the number of duplicates within their results prior to screening [135,136,137,138]. Techniques vary in their efficacy, sensitivity, and specificity (Table 2) [136, 138]. Knowing which method is used enables readers to evaluate the process and understand to what extent these techniques may have removed false positive duplicates [138]. Authors should describe and cite any software or technique used, when applicable. If duplicates were removed manually, authors should include a description.


The screening process was conducted independently by two reviewers (SCR and OLA). Citations were downloaded into Endnote software (version X7.3.1) and duplicates deleted. Records were screened by title and abstract. Potentially relevant articles were identified for further full-text screening (SCR and OLA). Discrepancies were resolved through discussion with a third reviewer (MC/DK/AS) if required.


Dirven et al. (2014) conducted a systematic review of PRO clinical trials in patient with brain tumours and demonstrated that HRQL can be used alongside overall and progression-free survival to inform clinical decision-making. One of the clinical trials included determined that the combination of concomitant and adjuvant temozolomide and radiotherapy has become standard care for newly diagnosed patients with glioblastoma [53]. This combination treatment led to significantly prolonged overall and progression-free survival, without negatively impacting HRQL in the long-term as measured with the EORTC QLQ-C30 questionnaire and Brain Cancer Module (BN-20) [53].


Sztankay et al. (2017) assessed HRQL during first-line chemotherapy with pametrexed and maintenance therapy (MT) among patients with advanced non-small cell lung cancer [73]. First-line chemotherapy for patients with advanced non-small cell lung cancer was shown to improve overall progression-free survival. However, as measured with the EORTC QLQ-C30 and EORTC QLQ-LC13, MT compared to first-line chemotherapy was associated with lower HRQL and improvements in nausea, vomiting, appetite loss, constipation and pain. This information presented alongside survival data, allowed patients and clinicians to make real-world informed joint decisions regarding treatment options.


Twenty-six studies were selected. The majority appeared in 2016 or after and were focused on methodological aspects; the applications mainly dealt with the documentation of skeletal findings and the identification or comparison of anatomical features and trauma. Most authors used commercial software packages, and an offline approach. Research is still quite heterogeneous concerning methods, terminology and quality of results, and proper validation is still lacking.